TY  - Type of reference 
TI  - Introduction of the Chicken Egg Chorioallontoic Membrane Test for Cosmetic Products in a Madagascan Context 
AU  - Eugénie Josephine 
AU  - Helga Rim Farasoa 
AU  - Rabarisoa Herilalaina 
AB  - Natural skin-care and wellness products are of increasing interest to consumers. For example, between 2015 and 2019, the global growth recorded for this market was up 10 to 11% [FER 21]. This situation offers a favourable opportunity for developing countries. However, in order to be able to offer products on the international market, these countries must comply with the regulations and standards imposed by international trade. Among these regulations, European legislation has banned animal model testing for cosmetics. [JOU 09]. Since a hen’s egg embryo is not considered an animal in most countries before 17 days of incubation, the use of the chorioallontoic membrane HET CAM test is a proposed alternative method. Furthermore, before 14 days, most agree that the embryo does not yet experience pain [RIB 16]. In a Madagascan context, where material and financial means are limited, the HET CAM method is an inexpensive and easy-to-perform procedure for testing cosmetics. After an evaluation of the possible appropriate techniques, natural brooding was chosen as the most suitable system for Madagascar. Some locally produced cosmetic creams were tested. Although HET CAM is widely recognized in many countries as a valid method for testing irritant products, tests on rabbits’ ears were performed for comparison purposes [BUD 21]. The good adaptability and flexibility of this technique has been demonstrated. In the Madagascan socio-economic context, this is an easy and beneficial technology transfer. 
DO  - 10.21494/ISTE.OP.2022.0861 
JF  - Science, Technology, Development 
KW  - Technology transfer,  Alternative cosmetic tests,  HET CAM,  Irritation,  Hyperaemia, Transfert de technologie,  tests cosmétiques alternatifs,  HET CAM,  irritation,  hypérémie,  
L1  - https://www.openscience.fr/IMG/pdf/iste_std22v2n1_6.pdf 
LA  - en 
PB  - ISTE OpenScience 
DA  - 2022/08/2 
SN  - 2752-6879 
TT  - Introduction du test sur Membrane Chorioallontoïque de l’oeuf de poule pour les produits cosmétiques dans un contexte malgache 
UR  - https://www.openscience.fr/Introduction-of-the-Chicken-Egg-Chorioallontoic-Membrane-Test-for-Cosmetic 
IS  - Issue 1 
VL  - 2 
ER  -